It
is the
tension 
between creativity and skepticism that has produced the stunning
and unexpected
findings of science. —Carl Sagan
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It is necessary to find an effective solution to the
ever-increasing problem of antibiotic resistant pathogens in the current medical
world. Based on preliminary research of ultrasound and
its ability to allow better permeation of small molecules through polymer
membranes, we are to investigate the said problem with the attempt to generate a
synergistic effect with ultrasound and antibiotics to inhibit bacteria growth. Method: Ultrasound of frequency 42kHz for
different time lengths were applied to E.
coli treated with spectinomycin at a non-inhibitory level. Conclusion: The
results obtained from the results proved to be inconclusive. Ultrasound of
frequency 42kHz applied up to an hour on
E. coli with a sub-inhibitory concentration of spectinomycin did not exhibit
significant and/or noticeable synergistic effects in inhibiting the bacteria
growth.
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Enhancement of Antibiotic Action with an Application of
Ultrasound 01/05/2007 |
