Blueberries: The Elixer of healthy Aging;  An in vitro study of the neuroprotective properties of fruit polyphenolics - Home
- Abstract
- Introduction
- Materials
- Methods
- Detailed Methods
- Results
- Calculations
- Discussion and Relevance
- Conclusion
- References
- Acknowledgements
- Project Info
Discussion and Relevents


Our results are quite promising, in that every experiment had results that were hypothesized. We can now state that the proper dosage is 0.1% blueberry extract, causing the correct increase of anthocyanins.

Pharmacological agents derived from natural products continue to form a significant component of modern drug discovery and may provide new avenues for therapeutic choice. The low toxicity associated with plant polyphenolics makes them very attractive for the treatment of a diverse array of chronic diseases. Understanding the pharmacological actions of fruits extracts could lead to the development of novel small molecule therapies for a number of debilitative age-related conditions. For example, additional neuroprotective applications of specific active compounds in blueberry extract could provide adjunct therapy in chronic neurodegenerative disorders such as Alzheimer's, where oxidative stress vulnerability may contribute to neuronal death and loss of function. Since Canada is one of the world's largest producers of blueberries with 47,660 tonnes produced in 2002, the isolation and development of pharmacological compounds derived from components in blueberries may provide opportunities to develop new biotechnology and expand export markets.




Copyright 2004 Gabriel Rigg, Michael Armson, David Dickinson.
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