Purpose

To find whether synergy exists between IP6 and PG490 drug concentration combinations in specific cancer cell lines.
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Inositol Hexaphosphate
IP6 is found in grain and inhibits cancer cell proliferation.
Triptolide
PG490 is found in a Chinese mushroom and induces cell death.

Synergy
Multiple drugs working together to produce a more effective result.

 

Project Information

Grade Grouping: 10-12
Team size: 3 people
Subject Area: Biology
Project Type: Experimental
Project Level: Advanced
Project Format: Traditional

Summary of Project: In this experiment, the investigator combined two drugs, inositol hexaphosphate and triptolide, to see whether they worked together to produce a synergistic effect in various cancer cell lines, so as to find a combination yielding maximum efficiency. Inositol hexaphosphate will inhibit cell proliferation, while triptolide will induce apoptosis among cells.

Description of Software used: Macromedia Dreamweaver MX, Macromedia Flash MX 2004, Macromedia Fireworks MX, Microsoft Word, Paint Shop Pro 7.04, Adobe Photoshop 7.0, Adobe ImageReady 7.0, Internet Explorer, Mozilla, K-Meleon, LeapFTP, SmartFTP, Notepad.

Hardware tools: Computer (PC & Laptop)
Source of idea: Group members
Special skills needed: HTML, CSS, Javascript, Flash, Image Editing.

Team Members: Colin Fung, Chris Cheung, Aaron Chow

Awards: Qualified for Canada-Wide National Science Fair 2004

Acknowledgements: Dr. M. Hitt, University of Alberta, Cross Cancer Institute


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copyright © 2004, Chris Cheung, Colin Fung, Aaron Chow